MicroRNA-21 Contributes to Liver Regeneration by Targeting PTEN

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MicroRNA-21 Contributes to Liver Regeneration by Targeting PTEN.

BACKGROUND Multiple microRNAs (miRNAs, miRs), including miR-21, have been documented to be critical regulators of liver regeneration, but the mechanism underlying their roles in hepatocyte proliferation and cell cycle progression is still far from understood. MATERIAL/METHODS miR-21 levels were determined using qRT-PCRs in mouse livers at 48 h after 70% partial hepatectomy (PH-48 h). Cell pro...

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ژورنال

عنوان ژورنال: Medical Science Monitor

سال: 2016

ISSN: 1643-3750

DOI: 10.12659/msm.896157